Titles are generally used when addressing people in a formal way. You can use signore  for a man or signora for woman followed by the surname. Some professionals are usually addressed by their professional titles such as professore / professoressa, dottore / dottoressa, ingegnere, and avvocato.

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Titles ending in -ore (signore, professore, dottore, etc.) drop the final e when followed by a surname: Buonasera, signore > Buonasera, Signor Gardini; Arrivederci, dottore > Arrivederci, dottor Rossi; Buongiorno, professore > Buongiorno, professor Salviati.